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Rapastinel，也被称为GLYX-13，是一种创新的N-甲基-D-天冬氨酸受体（NMDAR）调节剂，其独特之处在于它具备部分激动剂的特性。 生物活性 酸位点� 的特性。靶点:NMDA,Rapastinel 是一种功能强大的认知增强剂,可促进海马突触片的长期增强(LTP)。 Rapastinel (GLYX-13) 是一种N-甲基-D-天冬氨酸受体 (NMDAR) 调节剂, 具有部分激动剂特性。 雷帕替奈 (Rapastinel)是一种新型抗抑郁药物，被批准作为治疗难治性重度抑郁症的辅助治疗药物。 它是一种中枢活性的、经静脉给药 (非口服)的酰胺化四肽，在NMDA受体复合物 (Emax 25%)的甘氨酸位点作为选择性的、弱的局部激动剂 (混合拮抗剂/激动剂)。
Rapastinel（GLYX-13、BV-102、TPPT-酰胺）是一种针对甘氨酸位点的 N-甲基-D-天冬氨酸受体（NMDAR）部分激动剂。 Rapastinel 具有持久的抗抑郁作用。 中文名称：雷帕替奈 英文名称：GLYX-13 CAS号：117928-94-6 分子式：C18H31N5O6 分子量：413.4686 三字母：Thr-Pro-Pro-Thr-NH2 单字母：TPPT-NH2 生物活性与药理作用 · 作用机制：GLYX13是一种靶向NMDAR的甘氨酸位点的部分激动剂，具有持久的抗抑郁作用。 Rapastinel (GLYX-13, BV-102, TPPT-amide) 是一种靶向 N-methyl-D-aspartate receptor (NMDAR) 的甘氨酸位点的部分激动剂。 Rapastinel 具有持久的抗抑郁作用。 Description：Rapastinel是一种具有甘氨酸位点部分激动剂性质的NMDA受体调节剂多肽，序列中含有4个氨基酸，Rapastinel具有潜力用于抑郁症的研究。 Rapatinel is a NMDA receptor regulator peptide with the nature of a Partial agonist at the glycine site, which contains four amino acids in its sequence.
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