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Over time, bones can become fragile and misshapen.

Paget's disease of bone often causes the body to produce too many blood vessels in the affected bones, increasing the risk of serious blood loss during an operation. Cuando la enfermedad ósea de paget ocurre en una zona en la que pasan nervios a través del hueso, como la columna vertebral o el cráneo, el sobrecrecimiento de los huesos puede comprimir y dañar los nervios, lo que provoca dolor, debilidad u hormigueo en el brazo o la pierna, o pérdida auditiva. Paget's disease of the breast is a rare form of breast cancer that affects the nipple Paget's disease of the breast often causes scaly or crusty skin on the nipple.

Los medicamentos para la osteoporosis (bisfosfonatos) constituyen el tratamiento más común para la enfermedad ósea de paget Aunque en general los bisfosfonatos se administran por inyección en una vena, se pueden administrar por vía oral. Treatment for paget's disease of the breast often involves surgery Other treatments may include radiation therapy and medicines, such as chemotherapy and hormone therapy.

Bland ki, et al., eds

Paget disease of the breast Comprehensive management of benign and malignant diseases Paget's clinical practice focuses on reconstructing patients after cancer, aiming to improve their quality of life in survivorship through the restoration of form and function. Osteoporosis, metabolic bone disease, paget's disease of the bone, hyperparathyroidism, hypoparathyroidism

影像学检查 骨变化可通过以下检查发现： X 线检查。 佩吉特骨病的第一个指征往往是出于其他原因进行 X 光检查时发现的异常。骨的 X 线图像可以显示骨分解、骨增大和该病特有畸形（例如长骨弯曲）的区域。 骨扫描。 做骨扫描时，医生会将放射性物质注射到您体内。这些物质会流动到骨上受累.

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